Free Download Dna Mutation & Genetic Disorders
Published 8/2024
MP4 | Video: h264, 1920x1080 | Audio: AAC, 44.1 KHz
Language: English | Size: 229.94 MB | Duration: 0h 52m
Human DNA Mutation and Disorders
What you'll learn
DNA Mutation
Types of Mutations
Inherited genetic disorders
Non-inherited genetic disorders
Requirements
genetics and Human Biology
Description
DNA is a remarkably precise medium for copying and storing biological information. It serves as a design for cellular machinery that permits cells, organs, and even whole organisms to work. The fidelity of DNA replication results from the action of hundreds of genes involved in proofreading and damage repair. All human cells can acquire genetic changes in their DNA all over life. Genetic mutations are changes to the DNA sequence that happen during cell division when the cells make copies of themselves. Mutations in the DNA can cause genetic illnesses such as cancer, or they could help humans better adapt to their environment over time. The endogenous reactive metabolites, therapeutic medicines, and an excess of environmental mutagens, such as UV rays all continuously damage DNA, compromising its integrity. One or more chromosomal alterations and point mutations at a single site (monogenic mutation) including deletions, duplications, and inversions illustrate such DNA mutations. Genetic conditions can occur when an altered gene is inherited from parents, which increases the risk of developing that particular condition, or some gene alterations can happen randomly. Moreover, symptoms of genetic conditions depend on which gene has a mutation. There are many different diseases and conditions caused by mutations. Some of the most common genetic conditions are Alzheimer's disease, some cancers, cystic fibrosis, Down syndrome, and sickle cell disease. Interestingly, scientists find that DNA mutations are more common than formerly thought. This course outlines the main DNA mutations that occur along the human genome and their influence on human health.
Overview
Section 1: Introduction
Lecture 1 DNA Mutation and Mutagens
Lecture 2 Mutation Types
Lecture 3 Genetic Disorders & Single Gene Inheritance
Lecture 4 Multifactorial Inheritance Disorders
Lecture 5 Chromosomal Abnormalities
Lecture 6 Mitochondrial Diseases & Non-Inherited Disorders
Biologists and Medical Students
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